:. Patents


Immunomodulating Probiotic Lactic Acid Bacteria
Source: World Intellectual Property Office (WIPO)
10/07/2008

  • Patent Number:
  • WO/2008/079009

  • Inventors:
  • ZUURENDONK, Peter Frederik [NL/NL]; Lammenschansweg 118, NL-2313 DR Leiden (NL).
    KLEEREBEZEM, Michiel [NL/NL]; Indira Ghandisingel 4, NL-6716 GG Ede (NL).
    SNEL, Johannes [NL/NL]; Diedenweg 34, NL-6703 GX Wageningen (NL).
    MARCO, Maria [US/NL]; Don Boscoweg 30, NL-6871 DH Renkum (NL).
    SAVELKOUL, Hubertus Franciscus Jozef [NL/NL]; Julianalaan 10, NL-6721 ES Bennekom (NL).

  • Applicant:
  • Campina Nederland Holding B.V. [NL/NL]; Hogeweg 9, NL-5301 LB Zaltbommel (NL) (All Except US).
    ZUURENDONK, Peter Frederik [NL/NL]; Lammenschansweg 118, NL-2313 DR Leiden (NL) (US Only).
    KLEEREBEZEM, Michiel [NL/NL]; Indira Ghandisingel 4, NL-6716 GG Ede (NL) (US Only).
    SNEL, Johannes [NL/NL]; Diedenweg 34, NL-6703 GX Wageningen (NL) (US Only).
    MARCO, Maria [US/NL]; Don Boscoweg 30, NL-6871 DH Renkum (NL) (US Only).
    SAVELKOUL, Hubertus Franciscus Jozef [NL/NL]; Julianalaan 10, NL-6721 ES Bennekom (NL) (US Only).

  • Publication Date: 
  • 03/07/2008

  • Application Number:
  • PCT/NL2007/050694

  • Filed:
  • 21/12/2007



    The present invention relates to immuno modulat ing probiotic lactic acid bacteria, to methods wherein the bacteria are used to reduce allergy, and to food products wherein the bacteria may be in incorporated to reduce allergy upon consumption of the product. Preferred probiotic lactic acid bacteria stimulate the Th1 and/or Th3 responses and/or represses Th2 responses as may be determined by the cytokine profiles that are induced in human peripheral blood mononuclear cells upon coincubation with the lactic acid bacteria.




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